Research

Students wishing to get involved in my research can contact me.

Staphylococcal Genomics and Adaptation – I am currently working on the genomics of the Staphylococci to reveal aspects of how they adapt to a variety of different hosts and environments

Role of mobile DNA in Staphylococcal evolution – I study mobile DNA such as pathogenicity islands and ICE elements and their contribution to the evolution of the bacteria

Metagenomics of Environmental Bacteria – I am currently involved in several metagenomics projects with undergraduate researchers, looking at the microbiome of the Mercy campus

Student Reading Skills in STEM – I mentor student researchers in the scholarship of student reading and peer led team learning

Incorporating Authentic Research into the Microbiology Curriculum – My goal is to incorporate genomics into the microbiology teaching lab class

Selected Posters, Panels, Oral Presentations

1. Vegas, N.* and Smyth, D. S. (2017) Microbiology of the built environment. The changing microbiome of Mercy College. Oral presentation by an Undergraduate Student. The American Society for Microbiology Annual Meeting. New Orleans, La. Accepted.
2. Seto, J., and Smyth, D. (2017). Using next generation sequencing technology to elucidate the microorganism diversity in different water sites in Brooklyn. The American Society for Microbiology Annual Meeting. New Orleans, La. Accepted.
3. Smyth, D.S. (2017) Improving Civic and Scientific Literacy through Scaffolded Thematic Classroom Research Experiences. The American Society for Microbiology Annual Meeting. New Orleans, La. Accepted.
4. Vegas, N.* and Smyth, D. S. (2017) Microbiology of the built environment. The changing microbiome of Mercy College. Oral presentation by an Undergraduate Student. The 25th Annual CSTEP Conference, Lake George, Bolton Landing, NY. Accepted.
5. Tumidajski, N*. and Smyth, D. S. (2017) Do antibiotic resistant Staphylococci from the University cafeteria harbor enterotoxins? Poster presentation by an Undergraduate Student. The 25th Annual CSTEP Conference, Lake George, Bolton Landing, NY. Accepted.
6. Porconi, B*., Surendran, G. and Smyth, D. S. (2017) The effect of benzethonium chloride and natural antibacterials on agr-dysfunctional Staphylococci. The 25th Annual CSTEP Conference, Lake George, Bolton Landing, NY. Accepted.
7. Smyth, D.S. (2016) Improving Civic and Scientific Literacy through Scaffolded Thematic Classroom Research Experiences. Poster Presentation. SENCER Summer Institute. July 28th to Aug 1st 2016. Roosevelt University, Chicago, IL. Submitted.
8. Ellison, I., & Smyth, D.S. (2016) How the Toilet Changed the World. Panel for World Toilet Day. November 18th, 2016. Mercy College, Dobbs Ferry, NY.
9. Vegas, N.* and Smyth, D. S. (2016) Microbiology of the built environment. The changing microbiome of Mercy College. Poster presentation by an Undergraduate Student. The 49th Annual Conference of the Metropolitan Association of College and University Biologists. October 29th 2016. SUNY Old Westbury, NY
10. Vegas, N.* and Smyth, D. S. (2016) Microbiology of the built environment. The changing microbiome of Mercy College. Oral presentation by an Undergraduate Student. The Annual Biomedical Research Conference for Minority Students. November 9th to 12th 2016. Tampa, Fl.
11. Tumidajski, N*. and Smyth, D. S. (2016) Do antibiotic resistant Staphylococci from the University cafeteria harbor enterotoxins? Poster presentation by an Undergraduate Student. The Annual Biomedical Research Conference for Minority Students. November 9th to 12th 2016. Tampa, Fl.
12. Mancini, D*. and Smyth, D. S. (2016) Exercising your immune system: A comparison of resistant Staphylococcus aureus populations in college gyms. Poster presentation by an Undergraduate Student. The Annual Biomedical Research Conference for Minority Students. November 9th to 12th 2016. Tampa, Fl.
13. Porconi, B*., Surendran, G. and Smyth, D. S. (2016) The effect of benzethonium chloride and natural antibacterials on agr-dysfunctional Staphylococci. Poster presentation by an Undergraduate Student. The 49th Annual Conference of the Metropolitan Association of College and University Biologists. October 29th 2016. SUNY Old Westbury, NY.
14. Porconi, B*., Surendran, G. and Smyth, D. S. (2016) The effect of benzethonium chloride and natural antibacterials on agr-dysfunctional Staphylococci. Poster presentation by an Undergraduate Student. The Annual Biomedical Research Conference for Minority Students. November 9th to 12th 2016. Tampa, Fl.
15. Elison, I., & Smyth, D.S. (2016) Summer of Zika. Social & Public Health Impact of the Zika Epidemic. Panel presentation. April 6th. Mercy College, Dobbs Ferry, NY.
16. Smyth, D.S. (2016) The Latest News on MRSA. Oral Presentation. April 19th From Ebola to Zika: Present and Emerging Infectious Diseases. A conference at Columbia University sponsored by the University Seminars, Population Biology #521
17. Smyth, D.S. (2016). Microbiology of the built environment: The changing microbiome or “staphome” of New York City College Campuses. February 22th. Invited talk at PACE University, New York, NY.
18. Matthews, A., Bilello, Maria-Elena, Smyth, D and But, J (2015). Back to Basics: Improving Reading in Dental Hygiene Courses. CDHA National Conference. Oct 29-31. Victoria, British Columbia.
19. Tumidajski, N.* Sullivan, K* and Smyth D. (2016). Just how prevalent are antibiotic resistant Staphylococci: A Study of the Differences Between Campus Cafeterias. Poster presentation by Undergraduate Students. The 5th Annual Westchester Undergraduate Research Conference. April 15th. Mercy College, Dobbs Ferry, NY
20. Mancini, D.*, Carcamo, T.A.* and Smyth D. (2016). Exercising Your Immune System: A Comparison of Resistant Staphylococcus aureus Populations in College Gyms. Poster presentation by Undergraduate Students. The 5th Annual Westchester Undergraduate Research Conference. April 15th. Mercy College, Dobbs Ferry, NY
21. Smyth, D.S. (2015) Careers in Teaching and Education. Panel Presentation. What you can be with a PhD, A Science and Technology Focused Career Convention. Oct 25th 2015. NYU Langone Medical Center, NYC.
22. Smyth, D.S., and But, J. (2015) When There is No College Reading. Oral Presentation. SENCER Regional Conference. Oct 16th 2015. New York City College of Technology, Brooklyn, NY.
23. Seto, J. and Smyth D.S. (2015). Using Technology both inside and outside the Classroom: How RNAseq, Metagenomics and Bioinformatics can be Combined as Both Teaching and Research Tools with Undergraduate Students. Oral Presentation. The 48th Annual Conference of the Metropolitan Association of College and University Biologists. November 7th 2015. Montclair State University, NJ.
24. Culhane, T.H., Elison, I., and Smyth, D.S. (2015) How the Toilet Changed the World. Panel for World Toilet Day. November 17th, 2015. Mercy College, Dobbs Ferry, NY.
25. Culhane, T.H., Elison, I., and Smyth, D.S. (2015) Gender, Water and Sanitation: Interlinkages in Sustainable Development. Panel. November 3rd, 2015. Mercy College, Dobbs Ferry, NY.
26. Fontaine, F.*, Seto, J. and Smyth, D. S. (2015) Using next generation sequencing technology to elucidate the microorganism diversity in different water sites in Brooklyn. Poster presentation by an Undergraduate Student. The 48th Annual Conference of the Metropolitan Association of College and University Biologists. November 7th 2015. Montclair State University, NJ.
27. Fontaine, F.*, Seto, J. and Smyth, D. S. (2015) Using next generation sequencing technology to elucidate the microorganism diversity in different water sites in Brooklyn. Poster presentation by an Undergraduate Student. The Annual Scientista Symposium. Oct 17th 2015. Microsoft Office, 11 Time Square, NY.
28. Hoyos, M.* and Smyth, D. S. (2015) Microbiology of the Built Environment: The changing microbiome of New York City College of Technology. Poster presentation by an Undergraduate Student. The 48th Annual Conference of the Metropolitan Association of College and University Biologists. November 7th 2015. Montclair State University, NJ.
29. Hoyos, M.* and Smyth, D. S. (2015) Microbiology of the Built Environment: The changing microbiome of New York City College of Technology. Poster presentation by an Undergraduate Student. The Annual Scientista Symposium. Oct 17th 2015. Microsoft Office, 11 Time Square, NY.
30. Smyth, D.S. The READ initiative. CUNY Assessment Seminar, John Jay, CUNY, March 2015.
31. Rasool, A*., and D.S. Smyth. (2014) Promoting Critical thinking Through Bloom’s Taxonomy in BIO 1101 Peer-led workshops. In proceedings of the Annual Conference, Peer-led Team Learning International Society. *Oral presentation by an undergraduate researcher
32. Fontaine, F.*, Lam, M., Tsang, W.P.K, and D. S. Smyth. Microbiology of the Built Environment: The changing microbiome of New York City College of Technology. In proceedings of the Annual Biomedical Research Conference for Minority Students. *Poster presentation by an undergraduate researcher.
33. Smyth, D.S. “The adaptability of the Staphylococci”. Queens College Seminar 2014 Series. Seminar presentation
34. Smyth, D.S. “Using Staphylococcus aureus as a Model Organism for Studying Bacterial Adaptation and Evolution”. Brooklyn College Seminar 2013 Series. Seminar presentation
35. Smyth, D.S. The intrinsic value of art and science. Panel presentation as part of the Underground Zero Project, July 2014, NYC.
36. Smyth, D.S. Lessons learned from bacterial networks. How to land and keep that academic job. New York Medical College. June 2014. NYMCPA Seminar Series. Seminar presentation
37. Emerging Trends in Biotech as part of the TECH U entrepreneurship symposium of Brooklyn Tech Triangle (http://vimeo.com/93374319). Panel presentation
38. “Women in Stem”. Presented as panelist on the challenges of being a woman in STEM in Spring 2014 at NYCCT.
39. But, J., Smyth, D.S. and LaBoy, H. (2014). Reading Effectively Across the Disciplines. The International Journal of Arts and Sciences’ conference. Harvard Medical School – Panel Presentation
40. Smyth, D. S. Reading Effectively Across the Disciplines – Focus on Biology (2014). The Teaching Professor Conference – Poster presentation
41. Rakov, A. V., LeRoy, C. E., Smyth, D. S., Luo, X., Ubukata, K., Dagan, R., Rudolph, K., Robinson, D. A. TN6078: A novel mobile genetic element discovered in pneumococcal outbreak strains has geography-specific invasive disease associations. In: Proceedings of the 8th International Symposium on Pneumococci and Pneumococcal Infections, Brazil 2012 – Poster presentation
42. Smyth DS, Wible M, Mendes RE, Labella A, Kafer JM, Torres VJ, Novick RP, and Shopsin B. agr function and mortality in nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus. In Proceedings of the 52nd ICAAC in San Francisco, Sept 9-12, 2012. Oral presentation by B Shopsin.
43. Smyth, D. S., E. J. Feil, W. J. Meaney, P. J. Hartigan, J. R. Fitzgerald, D. A. Robinson, C. J. Smyth, and M. C. Enright. (2004) Staphylococcus aureus isolated from cows, goats, sheep, rabbits and chickens: Genotypic variation as revealed using molecular typing techniques. In: Proceeding of the 5th World Congress Foodborne Infections and Intoxications, Berlin, Germany 6th to 12th June 2004 – Oral Presentation
44. Smyth, D. S., J. H. Song, M. C. Enright, H. de Lencastre, and D. A. Robinson. (2008) Global phylogeny of the ST239–MRSA–III clone. In: Proceeding of the 13th International Symposium on Staphylococci and Staphylococcal Infections, Cairns, Australia – Oral presentation by DA Robinson
45. Smyth, D. S., P. J. Hartigan, W. J. Meaney and C. J. Smyth. (2003) Application of multiplex PCR to determine the frequencies of classical and novel Staphylococcal enterotoxins in strains associated with mastitis. In: Proceedings of the 57th Annual Conference of the Association of Veterinary Teachers and Research Workers, Scarborough, 14-16th April 2003 – Oral Presentation
46. Smyth, D. S., P. J. Hartigan, W. J. Meaney and C. J. Smyth. (2003) Application of multiplex PCR to detect novel enterotoxin genes in strains of Staphylococcus aureus from goats, sheep, pigs and rabbits. In: Proceedings of the 1st FEMS Congress of European Microbiologists, Slovenia, June 29th to July 3rd 2003 – Oral presentation
47. Smyth, D. S., P. J. Hartigan, W. J. Meaney and C. J. Smyth. (2002) Novel and putative exotoxin genes in strains of Staphylococcus aureus from bovine mastitis. In: Proceedings of the 32nd Annual Food Science and Technology Research Conference, UCC, Cork, Ireland, September 2002 – Poster presentation
48. Smyth, D. S., P. J. Hartigan, W. J. Meaney and C. J. Smyth. (2002) Frequencies of novel and putative exotoxin genes in strains of Staphylococcus aureus. In: Proceedings of the 10th International Symposium on Staphylococci and Staphylococcal Infections, Tsukuba, Japan 2002 – Poster presentation

* Undergraduate author

Publications
Peer Reviewed Publications

1. But, J., Brown, PA and Smyth, DS. Reading Effectively Across the Disciplines (READ): A Strategy to Improve Student Success. Insight: A Journal of Scholarly Teaching 2017(12):30-50.
2. Martínez-Rubio R, Quiles-Puchalt N, Martí M, Humphrey S, Ram G, Smyth D, Chen J, Novick RP, Penadés JR. Phage-inducible islands in the Gram-positive cocci. ISME J. 2016 Dec 13. PubMed PMID: 27959343.
3. Rose HR, Holzman RS, Altman DR, Smyth DS, Wasserman GA, Kafer JM, Wible M, Mendes RE, Torres VJ, Shopsin B. Cytotoxic Virulence Predicts Mortality in Nosocomial Pneumonia Due to Methicillin-Resistant Staphylococcus aureus. J Infect Dis. 2015 Jun 15;211(12):1862-74. PubMed PMID: 25298028.
4. Mendes RE, Deshpande LM, Smyth DS, Shopsin B, Farrell DJ, Jones RN. Characterization of methicillin-resistant Staphylococcus aureus strains recovered from a phase IV clinical trial for linezolid versus vancomycin for treatment of nosocomial pneumonia. J Clin Microbiol. 2012 Nov;50(11):3694-702. PubMed PMID: 22972817.
5. Smyth DS, Kafer JM, Wasserman GA, Velickovic L, Mathema B, Holzman RS, Knipe TA, Becker K, von Eiff C, Peters G, Chen L, Kreiswirth BN, Novick RP, Shopsin B. Nasal carriage as a source of agr-defective Staphylococcus aureus bacteremia. J Infect Dis. 2012 Oct;206(8):1168-77. PubMed PMID: 22859823.
6. Chen L, Shopsin B, Zhao Y, Smyth D, Wasserman GA, Fang C, Liu L, Kreiswirth BN. Real-time nucleic acid sequence-based amplification assay for rapid detection and quantification of agr functionality in clinical Staphylococcus aureus isolates. J Clin Microbiol. 2012 Mar;50(3):657-61. PubMed PMID: 22219302.
7. Smyth DS, Wong A, Robinson DA. Cross-species spread of SCCmec IV subtypes in staphylococci. Infect Genet Evol. 2011 Mar;11(2):446-53. doi: 10.1016/j.meegid.2010.12.005. PubMed PMID: 21172458.
8. Guinane CM, Ben Zakour NL, Tormo-Mas MA, Weinert LA, Lowder BV, Cartwright RA, Smyth DS, Smyth CJ, Lindsay JA, Gould KA, Witney A, Hinds J, Bollback JP, Rambaut A, Penadés JR, Fitzgerald JR. Evolutionary genomics of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation. Genome Biol Evol. 2010 Jul 12;2:454-66. PubMed PMID: 20624747.
9. Chen L, Mediavilla JR, Smyth DS, Chavda KD, Ionescu R, Roberts RB, Robinson DA, Kreiswirth BN. Identification of a novel transposon (Tn6072) and a truncated staphylococcal cassette chromosome mec element in methicillin-resistant Staphylococcus aureus ST239. Antimicrob Agents Chemother. 2010 Aug;54(8):3347-54. PubMed PMID: 20479198.
10. Smyth DS, McDougal LK, Gran FW, Manoharan A, Enright MC, Song JH, de Lencastre H, Robinson DA. Population structure of a hybrid clonal group of methicillin-resistant Staphylococcus aureus, ST239-MRSA-III. PLoS One. 2010 Jan 5;5(1):e8582. PubMed PMID: 20062529.
11. Wong A, Reddy SP, Smyth DS, Aguero-Rosenfeld ME, Sakoulas G, Robinson DA. Polyphyletic emergence of linezolid-resistant staphylococci in the United States. Antimicrob Agents Chemother. 2010 Feb;54(2):742-8. PubMed PMID: 19933808.
12. Smyth DS, Robinson DA. Integrative and sequence characteristics of a novel genetic element, ICE6013, in Staphylococcus aureus. J Bacteriol. 2009 Oct;191(19):5964-75. PubMed PMID: 19648240.
13. Smyth DS, Feil EJ, Meaney WJ, Hartigan PJ, Tollersrud T, Fitzgerald JR, Enright MC, Smyth CJ. Molecular genetic typing reveals further insights into the diversity of animal-associated Staphylococcus aureus. J Med Microbiol. 2009 Oct;58(Pt 10):1343-53. PubMed PMID: 19528163.
14. Moise PA, Smyth DS, Robinson DA, El-Fawal N, McCalla C, Sakoulas G. Genotypic and phenotypic relationships among methicillin-resistant Staphylococcus aureus from three multicentre bacteremia studies. J Antimicrob Chemother. 2009 May;63(5):873-6. PubMed PMID: 19261624.
15. Collery MM, Smyth DS, Tumilty JJ, Twohig JM, Smyth CJ. Associations between enterotoxin gene cluster types egc1, egc2 and egc3, agr types, enterotoxin and enterotoxin-like gene profiles, and molecular typing characteristics of human nasal carriage and animal isolates of Staphylococcus aureus. J Med Microbiol. 2009 Jan;58(Pt 1):13-25. PubMed PMID: 19074649.
16. McCalla C, Smyth DS, Robinson DA, Steenbergen J, Luperchio SA, Moise PA, Fowler VG Jr, Sakoulas G. Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2008 Sep;52(9):3441-3. PubMed PMID: 18606839.
17. Collery MM, Smyth DS, Twohig JM, Shore AC, Coleman DC, Smyth CJ. Molecular typing of nasal carriage isolates of Staphylococcus aureus from an Irish university student population based on toxin gene PCR, agr locus types and multiple locus, variable number tandem repeat analysis. J Med Microbiol. 2008 Mar;57(Pt 3):348-58. PubMed PMID: 18287299.
18. Guinane CM, Sturdevant DE, Herron-Olson L, Otto M, Smyth DS, Villaruz AE, Kapur V, Hartigan PJ, Smyth CJ, Fitzgerald JR. Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health. J Infect Dis. 2008 Jan 15;197(2):205-13. PubMed PMID: 18177250.
19. Moise PA, Smyth DS, El-Fawal N, Robinson DA, Holden PN, Forrest A, Sakoulas G. Microbiological effects of prior vancomycin use in patients with methicillin-resistant Staphylococcus aureus bacteremia. J Antimicrob Chemother. 2008 Jan;61(1):85-90. PubMed PMID: 18042628.
20. O’Neill E, Pozzi C, Houston P, Smyth D, Humphreys H, Robinson DA, O’Gara JP. Association between methicillin susceptibility and biofilm regulation in Staphylococcus aureus isolates from device-related infections. J Clin Microbiol. 2007 May;45(5):1379-88. PubMed PMID: 17329452
21. Smyth DS, Meaney WJ, Hartigan PJ, Smyth CJ. Occurrence of ssl genes in isolates of Staphylococcus aureus from animal infection. J Med Microbiol. 2007 Mar;56(Pt 3):418-25. PubMed PMID: 17314375.
22. Smyth DS, Kennedy J, Twohig J, Miajlović H, Bolton D, Smyth CJ. Staphylococcus aureus isolates from Irish domestic refrigerators possess novel enterotoxin and enterotoxin-like genes and are clonal in nature. J Food Prot. 2006 Mar;69(3):508-15. PubMed PMID: 16541679.
23. Smyth DS, Hartigan PJ, Meaney WJ, Fitzgerald JR, Deobald CF, Bohach GA, Smyth CJ. Superantigen genes encoded by the egc cluster and SaPIbov are predominant among Staphylococcus aureus isolates from cows, goats, sheep, rabbits and poultry. J Med Microbiol. 2005 Apr;54(Pt 4):401-11. PubMed PMID: 15770028.

Book Chapter

Smyth, D. S., and D.A. Robinson. (2010). Population genetics of Staphylococcus. In Bacterial Population Genetics in Infectious Disease, Edited by D. Ashley Robinson, Daniel Falush and Edward J. Feil. John Wiley & Sons, Inc.

Other Publications

1. Smyth, D.S. (2016). How mighty microbes and genomics can be used to make biology relevant to our students. Published in the Fall Newsletter of the Empire State Association of Two Year College Biologists.
2. Smyth, D. S (2014). Antibacterials In Building Products: The Good, The Bad and the Downright Ugly. Available from: http://www.healthybuilding.net/news/2014/11/19/antibacterials-in-building-products-the-good-the-bad-…